JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.
Identifieur interne : 000805 ( Main/Exploration ); précédent : 000804; suivant : 000806JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.
Auteurs : Doyle Yang [États-Unis] ; Brandon Keys [États-Unis] ; David J Conti [États-Unis] ; Llewellyn Foulke [États-Unis] ; Kathleen Stellrecht [États-Unis] ; Linda Cook [États-Unis] ; Reynold I. Lopez-Soler [États-Unis]Source :
- Transplant infectious disease : an official journal of the Transplantation Society [ 1399-3062 ] ; 2017.
Descripteurs français
- KwdFr :
- Acide mycophénolique (administration et posologie), Acide mycophénolique (effets indésirables), Acide mycophénolique (usage thérapeutique), Adulte d'âge moyen (MeSH), Biopsie (MeSH), Créatinine (sang), Défaillance rénale chronique (chirurgie), Humains (MeSH), Immunoglobulines par voie veineuse (administration et posologie), Immunoglobulines par voie veineuse (usage thérapeutique), Immunosuppresseurs (administration et posologie), Immunosuppresseurs (effets indésirables), Immunosuppresseurs (usage thérapeutique), Immunosuppression thérapeutique (effets indésirables), Incidence (MeSH), Infections à polyomavirus (anatomopathologie), Infections à polyomavirus (diagnostic), Infections à polyomavirus (virologie), Infections à polyomavirus (épidémiologie), Isoxazoles (administration et posologie), Isoxazoles (effets indésirables), Isoxazoles (usage thérapeutique), Léflunomide (MeSH), Mâle (MeSH), Néphrite (anatomopathologie), Néphrite (diagnostic), Néphrite (virologie), Néphrite (épidémiologie), Rejet du greffon (anatomopathologie), Rejet du greffon (traitement médicamenteux), Rejet du greffon (virologie), Réaction de polymérisation en chaîne (MeSH), Sirolimus (administration et posologie), Sirolimus (effets indésirables), Sirolimus (usage thérapeutique), Tacrolimus (administration et posologie), Tacrolimus (effets indésirables), Tacrolimus (usage thérapeutique), Tests de la fonction rénale (MeSH), Transplantation homologue (effets indésirables), Transplantation rénale (effets indésirables), Virus BK (isolement et purification), Virus BK (pathogénicité), Virus JC (isolement et purification), Virus JC (pathogénicité), Virémie (diagnostic), Virémie (virologie), Virémie (épidémiologie).
- MESH :
- administration et posologie : Acide mycophénolique, Immunoglobulines par voie veineuse, Immunosuppresseurs, Isoxazoles, Sirolimus, Tacrolimus.
- anatomopathologie : Infections à polyomavirus, Néphrite, Rejet du greffon.
- chirurgie : Défaillance rénale chronique.
- diagnostic : Infections à polyomavirus, Néphrite, Virémie.
- effets indésirables : Acide mycophénolique, Immunosuppresseurs, Immunosuppression thérapeutique, Isoxazoles, Sirolimus, Tacrolimus, Transplantation homologue, Transplantation rénale.
- isolement et purification : Virus BK, Virus JC.
- pathogénicité : Virus BK, Virus JC.
- sang : Créatinine.
- traitement médicamenteux : Rejet du greffon.
- usage thérapeutique : Acide mycophénolique, Immunoglobulines par voie veineuse, Immunosuppresseurs, Isoxazoles, Sirolimus, Tacrolimus.
- virologie : Infections à polyomavirus, Néphrite, Rejet du greffon, Virémie.
- épidémiologie : Infections à polyomavirus, Néphrite, Virémie.
- Adulte d'âge moyen, Biopsie, Humains, Incidence, Léflunomide, Mâle, Réaction de polymérisation en chaîne, Tests de la fonction rénale.
English descriptors
- KwdEn :
- BK Virus (isolation & purification), BK Virus (pathogenicity), Biopsy (MeSH), Creatinine (blood), Graft Rejection (drug therapy), Graft Rejection (pathology), Graft Rejection (virology), Humans (MeSH), Immunoglobulins, Intravenous (administration & dosage), Immunoglobulins, Intravenous (therapeutic use), Immunosuppression (adverse effects), Immunosuppressive Agents (administration & dosage), Immunosuppressive Agents (adverse effects), Immunosuppressive Agents (therapeutic use), Incidence (MeSH), Isoxazoles (administration & dosage), Isoxazoles (adverse effects), Isoxazoles (therapeutic use), JC Virus (isolation & purification), JC Virus (pathogenicity), Kidney Failure, Chronic (surgery), Kidney Function Tests (MeSH), Kidney Transplantation (adverse effects), Leflunomide (MeSH), Male (MeSH), Middle Aged (MeSH), Mycophenolic Acid (administration & dosage), Mycophenolic Acid (adverse effects), Mycophenolic Acid (therapeutic use), Nephritis (diagnosis), Nephritis (epidemiology), Nephritis (pathology), Nephritis (virology), Polymerase Chain Reaction (MeSH), Polyomavirus Infections (diagnosis), Polyomavirus Infections (epidemiology), Polyomavirus Infections (pathology), Polyomavirus Infections (virology), Sirolimus (administration & dosage), Sirolimus (adverse effects), Sirolimus (therapeutic use), Tacrolimus (administration & dosage), Tacrolimus (adverse effects), Tacrolimus (therapeutic use), Transplantation, Homologous (adverse effects), Viremia (diagnosis), Viremia (epidemiology), Viremia (virology).
- MESH :
- chemical , administration & dosage : Immunoglobulins, Intravenous, Immunosuppressive Agents, Isoxazoles, Mycophenolic Acid, Sirolimus, Tacrolimus.
- chemical , adverse effects : Immunosuppressive Agents, Isoxazoles, Mycophenolic Acid, Sirolimus, Tacrolimus.
- chemical , blood : Creatinine.
- adverse effects : Immunosuppression, Kidney Transplantation, Transplantation, Homologous.
- diagnosis : Nephritis, Polyomavirus Infections, Viremia.
- drug therapy : Graft Rejection.
- epidemiology : Nephritis, Polyomavirus Infections, Viremia.
- isolation & purification : BK Virus, JC Virus.
- pathogenicity : BK Virus, JC Virus.
- pathology : Graft Rejection, Nephritis, Polyomavirus Infections.
- surgery : Kidney Failure, Chronic.
- chemical , therapeutic use : Immunoglobulins, Intravenous, Immunosuppressive Agents, Isoxazoles, Mycophenolic Acid, Sirolimus, Tacrolimus.
- virology : Graft Rejection, Nephritis, Polyomavirus Infections, Viremia.
- Biopsy, Humans, Incidence, Kidney Function Tests, Leflunomide, Male, Middle Aged, Polymerase Chain Reaction.
Abstract
JC polyomavirus-associated nephropathy (JC-PVAN) is a rare but challenging cause of renal dysfunction. We report JC-PVAN in a renal allograft recipient and highlight the obstacles in definitive diagnosis of this disease entity. A deceased-donor renal transplant recipient was diagnosed with JC polyomavirus nephritis 4 years after transplantation. Immunosuppressive agents were subsequently reduced, resulting in an initial stabilization of renal function. We present this interesting case and discuss the challenges with diagnosing and treating this rare entity.
DOI: 10.1111/tid.12654
PubMed: 28036142
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Rejection (virology)</term><term>Humans (MeSH)</term><term>Immunoglobulins, Intravenous (administration & dosage)</term><term>Immunoglobulins, Intravenous (therapeutic use)</term><term>Immunosuppression (adverse effects)</term><term>Immunosuppressive Agents (administration & dosage)</term><term>Immunosuppressive Agents (adverse effects)</term><term>Immunosuppressive Agents (therapeutic use)</term><term>Incidence (MeSH)</term><term>Isoxazoles (administration & dosage)</term><term>Isoxazoles (adverse effects)</term><term>Isoxazoles (therapeutic use)</term><term>JC Virus (isolation & purification)</term><term>JC Virus (pathogenicity)</term><term>Kidney Failure, Chronic (surgery)</term><term>Kidney Function Tests (MeSH)</term><term>Kidney Transplantation (adverse effects)</term><term>Leflunomide (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Mycophenolic Acid (administration & dosage)</term><term>Mycophenolic Acid (adverse effects)</term><term>Mycophenolic Acid (therapeutic use)</term><term>Nephritis (diagnosis)</term><term>Nephritis (epidemiology)</term><term>Nephritis (pathology)</term><term>Nephritis (virology)</term><term>Polymerase Chain Reaction (MeSH)</term><term>Polyomavirus Infections (diagnosis)</term><term>Polyomavirus Infections (epidemiology)</term><term>Polyomavirus Infections (pathology)</term><term>Polyomavirus Infections (virology)</term><term>Sirolimus (administration & dosage)</term><term>Sirolimus (adverse effects)</term><term>Sirolimus (therapeutic use)</term><term>Tacrolimus (administration & dosage)</term><term>Tacrolimus (adverse effects)</term><term>Tacrolimus (therapeutic use)</term><term>Transplantation, Homologous (adverse effects)</term><term>Viremia (diagnosis)</term><term>Viremia (epidemiology)</term><term>Viremia (virology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acide mycophénolique (administration et posologie)</term><term>Acide mycophénolique (effets indésirables)</term><term>Acide mycophénolique (usage thérapeutique)</term><term>Adulte d'âge moyen (MeSH)</term><term>Biopsie (MeSH)</term><term>Créatinine (sang)</term><term>Défaillance rénale chronique (chirurgie)</term><term>Humains (MeSH)</term><term>Immunoglobulines par voie veineuse (administration et posologie)</term><term>Immunoglobulines par voie veineuse (usage thérapeutique)</term><term>Immunosuppresseurs (administration et posologie)</term><term>Immunosuppresseurs (effets indésirables)</term><term>Immunosuppresseurs (usage thérapeutique)</term><term>Immunosuppression thérapeutique (effets indésirables)</term><term>Incidence (MeSH)</term><term>Infections à polyomavirus (anatomopathologie)</term><term>Infections à polyomavirus (diagnostic)</term><term>Infections à polyomavirus (virologie)</term><term>Infections à polyomavirus (épidémiologie)</term><term>Isoxazoles (administration et posologie)</term><term>Isoxazoles (effets indésirables)</term><term>Isoxazoles (usage thérapeutique)</term><term>Léflunomide (MeSH)</term><term>Mâle (MeSH)</term><term>Néphrite (anatomopathologie)</term><term>Néphrite (diagnostic)</term><term>Néphrite (virologie)</term><term>Néphrite (épidémiologie)</term><term>Rejet du greffon (anatomopathologie)</term><term>Rejet du greffon (traitement médicamenteux)</term><term>Rejet du greffon (virologie)</term><term>Réaction de polymérisation en chaîne (MeSH)</term><term>Sirolimus (administration et posologie)</term><term>Sirolimus (effets indésirables)</term><term>Sirolimus (usage thérapeutique)</term><term>Tacrolimus (administration et posologie)</term><term>Tacrolimus (effets indésirables)</term><term>Tacrolimus (usage thérapeutique)</term><term>Tests de la fonction rénale (MeSH)</term><term>Transplantation homologue (effets indésirables)</term><term>Transplantation rénale (effets indésirables)</term><term>Virus BK (isolement et purification)</term><term>Virus BK (pathogénicité)</term><term>Virus JC (isolement et purification)</term><term>Virus JC 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veineuse</term><term>Immunosuppresseurs</term><term>Isoxazoles</term><term>Sirolimus</term><term>Tacrolimus</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Immunosuppression</term><term>Kidney Transplantation</term><term>Transplantation, Homologous</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Infections à polyomavirus</term><term>Néphrite</term><term>Rejet du greffon</term></keywords><keywords scheme="MESH" qualifier="chirurgie" xml:lang="fr"><term>Défaillance rénale chronique</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Nephritis</term><term>Polyomavirus Infections</term><term>Viremia</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à polyomavirus</term><term>Néphrite</term><term>Virémie</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Graft Rejection</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Acide mycophénolique</term><term>Immunosuppresseurs</term><term>Immunosuppression thérapeutique</term><term>Isoxazoles</term><term>Sirolimus</term><term>Tacrolimus</term><term>Transplantation homologue</term><term>Transplantation rénale</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Nephritis</term><term>Polyomavirus Infections</term><term>Viremia</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>BK Virus</term><term>JC Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus BK</term><term>Virus JC</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>BK Virus</term><term>JC Virus</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus BK</term><term>Virus JC</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Graft Rejection</term><term>Nephritis</term><term>Polyomavirus Infections</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Créatinine</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Kidney Failure, Chronic</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Immunoglobulins, Intravenous</term><term>Immunosuppressive Agents</term><term>Isoxazoles</term><term>Mycophenolic Acid</term><term>Sirolimus</term><term>Tacrolimus</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Rejet du greffon</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide mycophénolique</term><term>Immunoglobulines par voie veineuse</term><term>Immunosuppresseurs</term><term>Isoxazoles</term><term>Sirolimus</term><term>Tacrolimus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à polyomavirus</term><term>Néphrite</term><term>Rejet du greffon</term><term>Virémie</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Graft Rejection</term><term>Nephritis</term><term>Polyomavirus Infections</term><term>Viremia</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à polyomavirus</term><term>Néphrite</term><term>Virémie</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biopsy</term><term>Humans</term><term>Incidence</term><term>Kidney Function Tests</term><term>Leflunomide</term><term>Male</term><term>Middle Aged</term><term>Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Biopsie</term><term>Humains</term><term>Incidence</term><term>Léflunomide</term><term>Mâle</term><term>Réaction de polymérisation en chaîne</term><term>Tests de la fonction rénale</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">JC polyomavirus-associated nephropathy (JC-PVAN) is a rare but challenging cause of renal dysfunction. We report JC-PVAN in a renal allograft recipient and highlight the obstacles in definitive diagnosis of this disease entity. A deceased-donor renal transplant recipient was diagnosed with JC polyomavirus nephritis 4 years after transplantation. Immunosuppressive agents were subsequently reduced, resulting in an initial stabilization of renal function. We present this interesting case and discuss the challenges with diagnosing and treating this rare entity.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28036142</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>14</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1399-3062</ISSN><JournalIssue CitedMedium="Internet"><Volume>19</Volume><Issue>2</Issue><PubDate><Year>2017</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Transplant infectious disease : an official journal of the Transplantation Society</Title><ISOAbbreviation>Transpl Infect Dis</ISOAbbreviation></Journal><ArticleTitle>JC polyomavirus nephropathy, a rare cause of transplant dysfunction: Case report and review of literature.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1111/tid.12654</ELocationID><Abstract><AbstractText>JC polyomavirus-associated nephropathy (JC-PVAN) is a rare but challenging cause of renal dysfunction. We report JC-PVAN in a renal allograft recipient and highlight the obstacles in definitive diagnosis of this disease entity. A deceased-donor renal transplant recipient was diagnosed with JC polyomavirus nephritis 4 years after transplantation. Immunosuppressive agents were subsequently reduced, resulting in an initial stabilization of renal function. We present this interesting case and discuss the challenges with diagnosing and treating this rare entity.</AbstractText><CopyrightInformation>© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Doyle</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Surgery, Albany Medical College, Albany, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keys</LastName><ForeName>Brandon</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Surgery, Albany Medical College, Albany, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>J Conti</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Division of Surgery, Section of Transplantation, Albany Medical Center, Albany, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Foulke</LastName><ForeName>Llewellyn</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Division of Pathology, Albany Medical Center, Albany, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stellrecht</LastName><ForeName>Kathleen</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Center for Immunology and Microbial Diseases, Albany Medical College, Albany, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cook</LastName><ForeName>Linda</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Laboratory Medicine, University of Washington, Seattle, WA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lopez-Soler</LastName><ForeName>Reynold I</ForeName><Initials>RI</Initials><AffiliationInfo><Affiliation>Division of Surgery, Section of Transplantation, Albany Medical Center, Albany, NY, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>02</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>Denmark</Country><MedlineTA>Transpl Infect Dis</MedlineTA><NlmUniqueID>100883688</NlmUniqueID><ISSNLinking>1398-2273</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016756">Immunoglobulins, Intravenous</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007166">Immunosuppressive Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007555">Isoxazoles</NameOfSubstance></Chemical><Chemical><RegistryNumber>AYI8EX34EU</RegistryNumber><NameOfSubstance UI="D003404">Creatinine</NameOfSubstance></Chemical><Chemical><RegistryNumber>G162GK9U4W</RegistryNumber><NameOfSubstance UI="D000077339">Leflunomide</NameOfSubstance></Chemical><Chemical><RegistryNumber>HU9DX48N0T</RegistryNumber><NameOfSubstance UI="D009173">Mycophenolic Acid</NameOfSubstance></Chemical><Chemical><RegistryNumber>W36ZG6FT64</RegistryNumber><NameOfSubstance UI="D020123">Sirolimus</NameOfSubstance></Chemical><Chemical><RegistryNumber>WM0HAQ4WNM</RegistryNumber><NameOfSubstance UI="D016559">Tacrolimus</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001739" MajorTopicYN="N">BK Virus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003404" MajorTopicYN="N">Creatinine</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006084" MajorTopicYN="N">Graft Rejection</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016756" MajorTopicYN="N">Immunoglobulins, Intravenous</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007165" MajorTopicYN="N">Immunosuppression</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007166" MajorTopicYN="N">Immunosuppressive Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007555" MajorTopicYN="N">Isoxazoles</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007577" MajorTopicYN="N">JC Virus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007676" MajorTopicYN="N">Kidney Failure, Chronic</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007677" MajorTopicYN="N">Kidney Function Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016030" MajorTopicYN="N">Kidney Transplantation</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000077339" MajorTopicYN="N">Leflunomide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009173" MajorTopicYN="N">Mycophenolic Acid</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009393" MajorTopicYN="N">Nephritis</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016133" MajorTopicYN="N">Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D027601" MajorTopicYN="N">Polyomavirus Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020123" MajorTopicYN="N">Sirolimus</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016559" MajorTopicYN="N">Tacrolimus</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014184" MajorTopicYN="N">Transplantation, Homologous</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014766" MajorTopicYN="N">Viremia</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">JC virus</Keyword><Keyword MajorTopicYN="N">nephropathy</Keyword><Keyword MajorTopicYN="N">polyomavirus</Keyword><Keyword MajorTopicYN="N">renal transplant</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>05</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>06</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>07</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>08</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2016</Year><Month>09</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>09</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>12</Month><Day>31</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>12</Month><Day>31</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28036142</ArticleId><ArticleId IdType="doi">10.1111/tid.12654</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Washington (État)</li><li>État de New York</li></region><settlement><li>Seattle</li></settlement><orgName><li>Université de Washington</li></orgName></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Yang, Doyle" sort="Yang, Doyle" uniqKey="Yang D" first="Doyle" last="Yang">Doyle Yang</name></region><name sortKey="Cook, Linda" sort="Cook, Linda" uniqKey="Cook L" first="Linda" last="Cook">Linda Cook</name><name sortKey="Foulke, Llewellyn" sort="Foulke, Llewellyn" uniqKey="Foulke L" first="Llewellyn" last="Foulke">Llewellyn Foulke</name><name sortKey="J Conti, David" sort="J Conti, David" uniqKey="J Conti D" first="David" last="J Conti">David J Conti</name><name sortKey="Keys, Brandon" sort="Keys, Brandon" uniqKey="Keys B" first="Brandon" last="Keys">Brandon Keys</name><name sortKey="Lopez Soler, Reynold I" sort="Lopez Soler, Reynold I" uniqKey="Lopez Soler R" first="Reynold I" last="Lopez-Soler">Reynold I. Lopez-Soler</name><name sortKey="Stellrecht, Kathleen" sort="Stellrecht, Kathleen" uniqKey="Stellrecht K" first="Kathleen" last="Stellrecht">Kathleen Stellrecht</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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